The National Center for Biotechnology Information (NCBI) Application Programming Interface (API) is a set of tools and services that allow researchers to access and retrieve data from the vast repositories of biological information maintained by NCBI. These repositories include genomic sequences, protein structures, and bibliographic information, among others. The NCBI API is particularly valuable for cancer research, providing seamless access to a multitude of databases, including PubMed, Gene, and Protein.