What is the Role of Cytokines in the Tumor Microenvironment?
The tumor microenvironment is a complex network of cancer cells, immune cells, fibroblasts, endothelial cells, and extracellular matrix. Cytokines play a pivotal role in this environment by affecting the behavior of both tumor cells and stromal cells. For instance, cytokines can promote the recruitment of immune cells to the tumor site, where they can either attack the tumor or be co-opted to support tumor growth and metastasis.
