Which enzymes are commonly overexpressed in cancer?
Several enzymes are commonly overexpressed in various types of cancer. Telomerase is one such enzyme that is highly active in cancer cells, allowing them to maintain their telomeres and avoid senescence. Cyclooxygenase-2 (COX-2) is another enzyme often upregulated in tumors, promoting inflammation and cancer progression. Additionally, enzymes involved in nucleotide synthesis, such as thymidylate synthase, are frequently overexpressed to support the increased proliferation of cancer cells.
