How can enzyme expression be targeted for cancer therapy?
Targeting enzyme expression represents a promising strategy in cancer therapy. Inhibitors of specific enzymes can be used to disrupt cancer cell metabolism and growth. For example, tyrosine kinase inhibitors have been developed to target aberrant kinase activity in cancer cells, leading to reduced proliferation and survival. Additionally, proteasome inhibitors block the degradation of pro-apoptotic factors, inducing cell death in cancer cells. By understanding the specific enzyme dysregulation in different cancers, more effective and targeted therapies can be developed.
