What Makes NODDI Different from Other Imaging Techniques?
While other imaging techniques like Diffusion Tensor Imaging (DTI) also provide information about tissue microstructure, NODDI offers several advantages. DTI primarily measures the diffusion of water molecules, which can be influenced by numerous factors including cellular density and membrane integrity. In contrast, NODDI specifically quantifies neurite density and orientation, providing a more detailed picture of the microenvironment. This specificity makes NODDI particularly useful for distinguishing between different types of tissue changes, such as those caused by cancer versus other neurological conditions.