NODDI can be employed to differentiate between benign and malignant tumors based on their microstructural characteristics. Malignant tumors typically have higher cellularity and more disorganized neurite structures compared to benign tumors. By quantifying these differences, NODDI can aid in the accurate classification of tumors, which is crucial for determining the appropriate treatment strategy. Additionally, NODDI can help identify the extent of tumor infiltration into surrounding brain tissue, providing valuable information for surgical planning.