What Role Do Actin Filaments Play in Tumor Cell Migration?
The migration of tumor cells is heavily dependent on the remodeling of the actin cytoskeleton. Actin filaments enable the formation of cellular protrusions such as lamellipodia and filopodia, which are essential for cell movement. These structures allow cancer cells to navigate through the extracellular matrix, a critical step in metastasis. The regulation of actin dynamics is thus a potential target for therapeutic intervention to inhibit metastasis.
