mitochondrial dysfunction

What Role Do Mitochondria Play in Apoptosis?

Mitochondria are central to the intrinsic pathway of apoptosis, a form of programmed cell death. They release pro-apoptotic factors such as cytochrome c when the cell is under stress, leading to the activation of caspases that dismantle the cell. Mitochondrial dysfunction can disrupt this process, allowing cancer cells to evade apoptosis and continue proliferating.

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