What technical skills are needed for developing cancer immunotherapies?
Developing cancer immunotherapies requires expertise in immunology, molecular biology, and cell biology. Techniques such as flow cytometry, ELISA, and mass cytometry are used to analyze immune cell populations and their functions. Understanding the mechanisms of immune checkpoints, such as PD-1/PD-L1 and CTLA-4, is crucial for designing checkpoint inhibitors. Additionally, skills in genetic engineering are necessary for developing CAR-T cell therapy, which involves modifying T cells to target cancer cells effectively.
