What Types of Glycosylation Changes Occur in Cancer?
Several types of glycosylation changes are commonly observed in cancer: - N-glycosylation: Alterations in the branching patterns of N-linked glycans. - O-glycosylation: Changes in the structure and length of O-linked glycans. - Sialylation: Increased sialic acid content, which can contribute to immune evasion. - Fucosylation: Changes in fucose residues, affecting cell signaling and adhesion.
