Several integrins have been implicated in different types of cancer. Notable examples include:
- Integrin αvβ3: Often associated with angiogenesis, the formation of new blood vessels, which is crucial for tumor growth and metastasis. - Integrin α6β4: Plays a significant role in the invasion and migration of cancer cells. - Integrin α5β1: Involved in the regulation of cell survival and proliferation.
