Which Motor Proteins are Most Relevant in Cancer Research?
Several motor proteins have been extensively studied in cancer research. Some of the key players include:
Kinesins: These are microtubule-associated motor proteins that play a role in chromosome segregation during mitosis. Overexpression of certain kinesins has been linked to poor prognosis in various cancers. Dyneins: Another class of microtubule-associated motor proteins, dyneins are involved in organelle transport and mitotic spindle positioning. Dysregulation of dyneins can affect cell division and contribute to cancer progression. Myosins: Actin-based motor proteins, myosins are involved in cell motility and cytokinesis. Altered myosin expression has been associated with increased invasiveness of cancer cells.
