Why Are Smac Mimetics Important in Cancer Therapy?
Cancer cells often acquire resistance to apoptosis, making them difficult to kill with conventional therapies. Smac mimetics can overcome this resistance by directly targeting the IAPs that prevent cell death. This makes them a promising class of drugs for treating various types of cancer, including those resistant to chemotherapy and radiation. Additionally, Smac mimetics can enhance the efficacy of other anticancer treatments by sensitizing cancer cells to apoptosis.
