There are multiple reasons for treatment failure in cancer: 1. Tumor Heterogeneity: Tumors are composed of diverse cell populations, some of which might be resistant to treatment. 2. Drug Resistance: Cancer cells can develop resistance to chemotherapy, targeted therapy, or immunotherapy. 3. Suboptimal Drug Delivery: Poor blood supply to the tumor can limit the effectiveness of chemotherapy. 4. Patient Factors: Age, general health, and genetic factors can influence the effectiveness of treatment.
