Can Endothelial Cells Be Targeted for Cancer Therapy?
Yes, endothelial cells can be targeted for cancer therapy. Anti-angiogenic therapies aim to inhibit the formation of new blood vessels, thereby starving the tumor of essential nutrients and oxygen. These therapies include the use of monoclonal antibodies, tyrosine kinase inhibitors, and other small molecules that specifically target endothelial cell function and angiogenic signaling pathways. For example, drugs targeting VEGF or its receptors can effectively reduce angiogenesis and tumor growth.
