Can Helper T Cells Be Targeted for Cancer Therapy?
Yes, targeting helper T cells is a promising approach in cancer therapy. Therapies include:
- Checkpoint Inhibitors: Drugs like pembrolizumab and nivolumab block checkpoint molecules (e.g., PD-1/PD-L1), thereby revitalizing exhausted helper T cells. - Cytokine Therapy: Administering cytokines like IL-2 can boost the proliferation and activation of helper T cells. - Cancer Vaccines: These vaccines aim to present tumor antigens to helper T cells in a way that triggers a robust anti-tumor response.
