How Do Isoflavones Interact with Estrogen Receptors?
Isoflavones can bind to estrogen receptors in the body, though they do so with less potency compared to natural estrogen. There are two main types of estrogen receptors, ER-alpha and ER-beta. Isoflavones have a higher affinity for ER-beta, which is believed to mediate many of their beneficial effects. This selective binding can lead to either estrogenic or anti-estrogenic actions depending on the tissue type and hormonal environment.