The PDB plays a pivotal role in cancer research by offering detailed structural information on proteins and other biomolecules involved in cancer progression and treatment. Researchers use this data to:
1. Identify Potential Drug Targets: By studying the structures of proteins involved in cancer pathways, such as kinases and oncogenes, scientists can identify potential targets for new cancer drugs. 2. Understand Protein Function and Interaction: The structural data helps elucidate how proteins interact with each other and with other molecules, which is crucial for understanding cancer mechanisms. 3. Design Targeted Therapies: With structural information, researchers can design drugs that specifically bind to cancer-related proteins, improving the efficacy and reducing the side effects of treatments.