circRNAs have been implicated in the regulation of multiple cellular processes that are crucial in cancer, including cell proliferation, apoptosis, migration, and invasion. Abnormal expression of circRNAs has been observed in various types of cancers, suggesting their potential role as oncogenes or tumor suppressors. For instance, some circRNAs can act as microRNA (miRNA) sponges, sequestering miRNAs and preventing them from repressing their target mRNAs. This can lead to the deregulation of gene expression pathways that promote tumorigenesis.
