What Are the Advantages of Using DNA-PK Inhibitors in Cancer Therapy?
There are several potential advantages to using DNA-PK inhibitors in cancer therapy:
Sensitization to Radiation and Chemotherapy: By inhibiting DNA repair, DNA-PK inhibitors can make cancer cells more susceptible to traditional treatments. Selective Targeting: Cancer cells often have higher levels of DNA damage and are more dependent on repair mechanisms compared to normal cells, potentially allowing for more selective targeting. Combination Therapy: DNA-PK inhibitors can be combined with other agents to enhance their efficacy, creating a synergistic effect.
