What are the challenges and future directions in RhoA research?
Despite significant advances, several challenges remain in the study of RhoA in cancer. One major challenge is the complexity of RhoA signaling networks and their context-dependent effects. Moreover, the development of highly specific and potent RhoA inhibitors is still in its early stages. Future research should focus on elucidating the precise mechanisms of RhoA in different cancer types and identifying biomarkers for patient stratification. Additionally, combination therapies that target multiple components of the RhoA pathway may offer synergistic effects and improve treatment outcomes.
