What Are the Challenges in Targeting Signal Interference?
Despite advances in targeted therapies, several challenges remain:
1. Drug Resistance: Cancer cells can develop resistance to targeted therapies through various mechanisms, including secondary mutations and activation of alternative pathways. 2. Tumor Heterogeneity: The genetic diversity within a tumor can make it difficult to target all cancer cells effectively. 3. Toxicity: Targeted therapies can have off-target effects, leading to toxicity and adverse side effects.
