What Are the Challenges of Targeting Immune Escape?
Despite the advances in immunotherapy, several challenges remain:
Resistance Mechanisms: Tumors can develop resistance to immunotherapies over time. Tumor Microenvironment: The tumor microenvironment can be highly immunosuppressive, making it difficult for immune cells to function effectively. Adverse Effects: Enhancing the immune response can sometimes lead to immune-related adverse events, including autoimmunity.