What are the Key Findings from Immune Landscape Mapping?
Immune landscape mapping has revealed several critical insights, including:
The presence of immune hotspots where immune cells are densely clustered. The identification of exhausted T cells that have reduced functionality due to chronic antigen exposure. The role of myeloid-derived suppressor cells (MDSCs) and regulatory T cells (Tregs) in immunosuppression within the TME. The discovery of distinct immune subtypes of tumors that correlate with different clinical outcomes and responses to therapy.