- Gleason Score 6 or less: Indicates that the cancer is well differentiated or low-grade. These cancers tend to grow slowly and are less likely to spread. - Gleason Score 7: This score is considered intermediate-risk. It is further divided into 3+4=7 and 4+3=7. A 3+4=7 score has a better prognosis than a 4+3=7 score. - Gleason Scores 8-10: These scores indicate high-grade cancer. The cancer cells are poorly differentiated, tend to grow more quickly, and are more likely to spread to other parts of the body.