The EWSR1 gene, or Ewing Sarcoma Breakpoint Region 1, encodes a protein that is a part of the TET (TLS/FUS, EWS, TAF15) family. This protein plays a crucial role in various cellular processes including RNA binding, transcriptional regulation, and gene expression. It is located on chromosome 22q12.2 and is known for its involvement in several fusion genes associated with cancer.