The Unfolded Protein Response (UPR) is a cellular stress response related to the endoplasmic reticulum (ER). It is activated in response to the accumulation of misfolded or unfolded proteins in the ER lumen. This response aims to restore normal function by halting protein translation, degrading misfolded proteins, and activating signaling pathways that lead to increased production of molecular chaperones involved in protein folding.
