TNF Receptor 1 (TNFR1) is a type of receptor that binds to Tumor Necrosis Factor (TNF), a cytokine involved in systemic inflammation and part of the immune system. TNFR1 is encoded by the TNFRSF1A gene and is ubiquitously expressed in various tissues. It plays a pivotal role in mediating the cellular response to TNF, which includes inflammation, cell survival, apoptosis, and necroptosis.
