Which cancers are currently being targeted by PROTACs?
PROTACs are being investigated for a variety of cancers, including those that have been difficult to treat with traditional therapies. Examples include prostate cancer, where PROTACs targeting the androgen receptor (AR) have shown promise, and breast cancer, where estrogen receptor (ER) degraders are being explored. PROTACs are also being developed to target other oncogenic proteins such as BCL-2 in hematological malignancies and KRAS in solid tumors.
