Are There Any Diagnostic Tools to Detect Efflux Transporters?
Yes, several diagnostic tools are available to detect and quantify the expression of efflux transporters in cancer cells: - Immunohistochemistry (IHC): This technique uses antibodies to detect specific efflux transporters in tissue samples. - Reverse Transcription Polymerase Chain Reaction (RT-PCR): This method quantifies the mRNA levels of efflux transporter genes. - Flow Cytometry: This technique can be used to measure the surface expression of efflux transporters on cancer cells.
